Stereological tools in biomedical research

Stereological tools in biomedical research.

Stereological studies are more and more frequent in literature, particularly in the development/evolution, pathology, and neurosciences areas. The stereology challenge is to understand the structural inner three-dimensional arrangement based on the analysis of the structure slices only showing two-dimensional information. Cavalieri and Scherle's methods to estimate volume, and Buffon's needle p...

Current bioinformatics tools in genomic biomedical research (Review).

On the advent of a completely assembled human genome, modern biology and molecular medicine stepped into an era of increasingly rich sequence database information and high-throughput genomic analysis. However, as sequence entries in the major genomic databases currently rise exponentially, the gap between available, deposited sequence data and analysis by means of conventional molecular biology...

Biomedical Imaging R&D: Advanced Tools for Cancer Research

Zebrafish development and regeneration: new tools for biomedical research.

Basic research in pattern formation is concerned with the generation of phenotypes and tissues. It can therefore lead to new tools for medical research. These include phenotypic screening assays, applications in tissue engineering, as well as general advances in biomedical knowledge. Our aim here is to discuss this emerging field with special reference to tools based on zebrafish developmental ...

Babies in biomedical research.

A few months ago, I had the pleasure of attending the traditional closing dinner of the 119th semiannual meeting of The Salt and Water Club*– held for the first time in Pittsburgh, and attended for the first time by a Club member from Cleveland (although elected while in New Haven). The dinner conversation–at first rather wide ranging– became focused when Mark Knepper of the NIH raised the casu...